TY  - JOUR
AU  - Popović, Ljiljana M.
AU  - Mitić, Nebojša R.
AU  - Mirić, Dijana
AU  - Bisevac, Boban
AU  - Mirić, Mirjana
AU  - Popović, Brankica
PY  - 2015
UR  - http://jakov.kpu.edu.rs/handle/123456789/666
AB  - Exercise induces a multitude of physiological and biochemical changes in blood affecting its redox status. Tissue damage resulting fromexercise induces activation of inflammatory cells followed by the increased activity ofmyeloperoxidase (MPO) in circulation. Vitamin C readily scavenges free radicals and may thereby prevent oxidative damage of important biological macromolecules. The aimof this study was to examine the effect of vitamin C supplementation on oxidative stress and neutrophil inflammatory response induced by acute and regular exercise. Experiment was conducted on acute exercise group (performing Bruce Treadmill Protocol (BTP)) and regular training group. Markers of lipid peroxidation, malondialdehyde (MDA), MPO activity, and vitamin C status were estimated at rest and after BTP (acute exercise group) and before and after vitamin C supplementation in both groups. Our results showed increased postexercise Asc in serum independently of vitamin supplementation. They also showed that vitamin C can significantly decrease postexercise MDA level in both experimental groups. Increased postexercise MPO activity has been found in both groups and was not affected by vitamin C supplementation. We concluded that vitamin C supplementation can suppress lipid peroxidation process during exercise but cannot affect neutrophil inflammatory response in either exercise group.
PB  - Hindawi Limited
T2  - Oxidative medicine and cellular longevity
T1  - Influence of Vitamin C Supplementation on Oxidative Stress and Neutrophil Inflammatory Response in Acute and Regular Exercise
DO  - 10.1155/2015/295497
ER  - 

@article{
author = "Popović, Ljiljana M. and Mitić, Nebojša R. and Mirić, Dijana and Bisevac, Boban and Mirić, Mirjana and Popović, Brankica",
year = "2015",
abstract = "Exercise induces a multitude of physiological and biochemical changes in blood affecting its redox status. Tissue damage resulting fromexercise induces activation of inflammatory cells followed by the increased activity ofmyeloperoxidase (MPO) in circulation. Vitamin C readily scavenges free radicals and may thereby prevent oxidative damage of important biological macromolecules. The aimof this study was to examine the effect of vitamin C supplementation on oxidative stress and neutrophil inflammatory response induced by acute and regular exercise. Experiment was conducted on acute exercise group (performing Bruce Treadmill Protocol (BTP)) and regular training group. Markers of lipid peroxidation, malondialdehyde (MDA), MPO activity, and vitamin C status were estimated at rest and after BTP (acute exercise group) and before and after vitamin C supplementation in both groups. Our results showed increased postexercise Asc in serum independently of vitamin supplementation. They also showed that vitamin C can significantly decrease postexercise MDA level in both experimental groups. Increased postexercise MPO activity has been found in both groups and was not affected by vitamin C supplementation. We concluded that vitamin C supplementation can suppress lipid peroxidation process during exercise but cannot affect neutrophil inflammatory response in either exercise group.",
publisher = "Hindawi Limited",
journal = "Oxidative medicine and cellular longevity",
title = "Influence of Vitamin C Supplementation on Oxidative Stress and Neutrophil Inflammatory Response in Acute and Regular Exercise",
doi = "10.1155/2015/295497"
}

Popović, L. M., Mitić, N. R., Mirić, D., Bisevac, B., Mirić, M.,& Popović, B.. (2015). Influence of Vitamin C Supplementation on Oxidative Stress and Neutrophil Inflammatory Response in Acute and Regular Exercise. in Oxidative medicine and cellular longevity
Hindawi Limited..
https://doi.org/10.1155/2015/295497

Popović LM, Mitić NR, Mirić D, Bisevac B, Mirić M, Popović B. Influence of Vitamin C Supplementation on Oxidative Stress and Neutrophil Inflammatory Response in Acute and Regular Exercise. in Oxidative medicine and cellular longevity. 2015;.
doi:10.1155/2015/295497 .

Popović, Ljiljana M., Mitić, Nebojša R., Mirić, Dijana, Bisevac, Boban, Mirić, Mirjana, Popović, Brankica, "Influence of Vitamin C Supplementation on Oxidative Stress and Neutrophil Inflammatory Response in Acute and Regular Exercise" in Oxidative medicine and cellular longevity (2015),
https://doi.org/10.1155/2015/295497 . .