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dc.creatorPopović, Ljiljana M.
dc.creatorMitić, Nebojša R.
dc.creatorMirić, Dijana
dc.creatorBisevac, Boban
dc.creatorMirić, Mirjana
dc.creatorPopović, Brankica
dc.date.accessioned2019-03-21T16:06:46Z
dc.date.available2019-03-21T16:06:46Z
dc.date.issued2015
dc.identifier.issn1942-0900
dc.identifier.urihttp://jakov.kpu.edu.rs/handle/123456789/666
dc.description.abstractExercise induces a multitude of physiological and biochemical changes in blood affecting its redox status. Tissue damage resulting fromexercise induces activation of inflammatory cells followed by the increased activity ofmyeloperoxidase (MPO) in circulation. Vitamin C readily scavenges free radicals and may thereby prevent oxidative damage of important biological macromolecules. The aimof this study was to examine the effect of vitamin C supplementation on oxidative stress and neutrophil inflammatory response induced by acute and regular exercise. Experiment was conducted on acute exercise group (performing Bruce Treadmill Protocol (BTP)) and regular training group. Markers of lipid peroxidation, malondialdehyde (MDA), MPO activity, and vitamin C status were estimated at rest and after BTP (acute exercise group) and before and after vitamin C supplementation in both groups. Our results showed increased postexercise Asc in serum independently of vitamin supplementation. They also showed that vitamin C can significantly decrease postexercise MDA level in both experimental groups. Increased postexercise MPO activity has been found in both groups and was not affected by vitamin C supplementation. We concluded that vitamin C supplementation can suppress lipid peroxidation process during exercise but cannot affect neutrophil inflammatory response in either exercise group.en
dc.publisherHindawi Limited
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/44007/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceOxidative medicine and cellular longevity
dc.titleInfluence of Vitamin C Supplementation on Oxidative Stress and Neutrophil Inflammatory Response in Acute and Regular Exerciseen
dc.typearticle
dc.rights.licenseBY
dc.citation.rankM21
dc.identifier.doi10.1155/2015/295497
dc.identifier.fulltexthttp://jakov.kpu.edu.rs/bitstream/id/2761/664.pdf
dc.identifier.scopus2-s2.0-84924599428
dc.identifier.wos000351087200001
dc.type.versionpublishedVersion


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