Chitosan microbeads for encapsulation of thyme (Thymus serpyllum L.) polyphenols
Samo za registrovane korisnike
2014
Autori
Trifković, Kata T.Milašinović, Nikola
Đorđević, Verica B.
Kalagasidis-Krušić, Melina T.
Knežević-Jugović, Zorica
Nedović, Viktor
Bugarski, Branko M.
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
In this work chitosan microbeads were prepared by emulsion technique and loaded with thyme polyphenols by diffusion from an external aqueous solution of Thymus serpyllum L. The effects of concentrations of chitosan (1.5-3% (w/v)) and GA (glutaraldehyde) (0.1-0.4% (v/v)), as a crosslinking agent on the main properties of microbeads were assessed. The obtained microgel beads from similar to 220 to similar to 790 mu m in diameter were exposed to controlled drying process at air (at 37 degrees C) after which they contracted to irregular shapes (similar to 70-230 mu m). The loading of dried microbeads with polyphenols was achieved by swelling in the acidic medium. The swelling rate of microbeads decreased with the increase in GA concentration. Upon this rehydration, thyme polypheriols were effectively encapsulated (active load of 66-114mg GAEg(beads)(-1)) and the microbeads recovered a spherical shape. Both, the increase in the amount of the crosslinking agent and the presence of polyphenol...s, contributed to a more pronounced surface roughness of microbeads. The release of encapsulated polyphenols in simulated gastrointestinal fluids was prolonged to 3 h.
Ključne reči:
Emulsion crosslinking technique / Chitosan microbeads / Polyphenols / MicroencapsulationIzvor:
Carbohydrate polymers, 2014, 111, 901-907Izdavač:
- Elsevier Sci Ltd, Oxford
Finansiranje / projekti:
- Razvoj novih inkapsulacionih i enzimskih tehnologija za proizvodnju biokatalizatora i biološki aktivnih komponenata hrane u cilju povećanja njene konkurentnosti, kvaliteta i bezbednosti (RS-46010)
- Sinteza i karakterizacija novih funkcionalnih polimera i polimernih nanokompozita (RS-172062)
DOI: 10.1016/j.carbpol.2014.05.053
ISSN: 0144-8617